NbCl5-Promoted Synthesis of 4-Aryl-3,4-dihydrocoumarins by Multicomponent Reaction

Artigo

Fecha

2012-11-01

Registro en:

Synthesis-stuttgart. Stuttgart: Georg Thieme Verlag Kg, v. 44, n. 21, p. 3361-3365, 2012.

0039-7881

http://hdl.handle.net/11449/41115

10.1055/s-0032-1317340

WOS:000310461400017

http://repositorioslatinoamericanos.uchile.cl/handle/2250/3912044

Autor

Universidade Estadual Paulista (Unesp)

Institución

Universidade Paulista Júlio de Mesquita Filho (Brasil)

Resumen

Substituted 4-aryl-3,4-dihydrocoumarins are synthesized from multicomponent reactions between phenols, dimethyl malonate, and aryl aldehydes catalyzed by niobium pentachloride. This new method is simple, cost-effective, and high-yielding, and can be conducted in acceptable reaction times.

Materias

niobium pentachloride

multicomponent reaction

coumarin derivatives

Lewis acid

phenols

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