Lithium thiazolidine-4-carboxylate: Synthesis, spectroscopic characterization and preliminary in vitro cytotoxic studies in human HeLa cells

dc.contributorCtr Univ Araraquara UNIARA
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T15:30:33Z
dc.date.accessioned2022-10-05T16:59:53Z
dc.date.available2014-05-20T15:30:33Z
dc.date.available2022-10-05T16:59:53Z
dc.date.created2014-05-20T15:30:33Z
dc.date.issued2008-12-01
dc.identifierSpectrochimica Acta Part A-molecular and Biomolecular Spectroscopy. Oxford: Pergamon-Elsevier B.V. Ltd, v. 71, n. 3, p. 929-931, 2008.
dc.identifier1386-1425
dc.identifierhttp://hdl.handle.net/11449/39905
dc.identifier10.1016/j.saa.2008.02.013
dc.identifierWOS:000261118400032
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/3910952
dc.description.abstractA new water-soluble lithium Salt of thiazolidine-4-carboxylic acid was synthesized and characterized by chemical and spectroscopic techniques, Elemental and mass spectrometric (ESI-MS) analyses of the solid compound fit to the composition LiC(4)H(6)NSO(2). (1)H, (13)C nuclear magnetic resonance (NMR). [(1)H-(15)N] NMR and infrared (IR) analyses permitted to elucidate the structure of the compound. Biological activity was evaluated by cytotoxic analysis using HeLa cells. Determination of cell death was assessed using a tetrazolium Salt colorimetric assay, which reflects the cells viability. (C) 2008 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherPergamon-Elsevier B.V. Ltd
dc.relationSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
dc.relation2.880
dc.relation0,648
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectThiazolidine-4-carboxylic acid
dc.subjectInfrared spectroscopy
dc.subjectNMR spectroscopy
dc.subjectCytotoxicity
dc.titleLithium thiazolidine-4-carboxylate: Synthesis, spectroscopic characterization and preliminary in vitro cytotoxic studies in human HeLa cells
dc.typeArtigo


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