dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-20T15:21:04Z | |
dc.date.accessioned | 2022-10-05T16:08:50Z | |
dc.date.available | 2014-05-20T15:21:04Z | |
dc.date.available | 2022-10-05T16:08:50Z | |
dc.date.created | 2014-05-20T15:21:04Z | |
dc.date.issued | 2006-08-01 | |
dc.identifier | Electroanalysis. Weinheim: Wiley-v C H Verlag Gmbh, v. 18, n. 15, p. 1457-1462, 2006. | |
dc.identifier | 1040-0397 | |
dc.identifier | http://hdl.handle.net/11449/32246 | |
dc.identifier | 10.1002/elan.200603534 | |
dc.identifier | WOS:000239719800003 | |
dc.identifier | 0000-0002-2296-1393 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/3904835 | |
dc.description.abstract | This work describes an electroanalytical method for determining gold(I) thiomalate, aurothiomalate, widely used for treatment of reumatoid arthiritis, using a screen-printed carbon electrode (SPCE). Aurothiomalate (AuTM) was determined indirectly at the same electrode by accumulating it first at -1.5 V vs. printed carbon. At this potential in the adsorbed state, the AuTM is reduced to Au(0), which is then oxidized at two steps at -0.22 V and +0.54 V on SPCE. Using optimized conditions of 60 s deposition time, -1.5 V (vs. printed carbon) accumulation potential, 100 mV s(-1) scan rate, linear calibration graphs can be obtained by monitoring the peak at +0.54 V for AuTM in HCl 0.1 mol L-1 from 1.43 x 10(-6) to 1.55 x 10(-4) mol L-1. A limit of detection obtained was 6.50 x 10(-7) mol L-1, and the relative standard deviation from five measurements of 3.0 x 10(-5) mol L-1 AuTM is 4.5%. The method was successfully applied for AuTM determination in human urine sample. | |
dc.language | eng | |
dc.publisher | Wiley-Blackwell | |
dc.relation | Electroanalysis | |
dc.relation | 2.851 | |
dc.relation | 0,692 | |
dc.rights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | sodium aurothiomalate | |
dc.subject | gold(I) thiolate determination | |
dc.subject | screen-printed electrode | |
dc.subject | gold-base drugs | |
dc.title | Anodic stripping voltammetric determination of aurothiomalate in urine using a screen-printed carbon electrode | |
dc.type | Artigo | |