Artigo
Development and validation of a HPLC method for standardization of herbal and commercial extracts of Myrcia uniflora
Fecha
2011-06-01Registro en:
Revista Brasileira de Farmacognosia. Sociedade Brasileira de Farmacognosia, v. 21, n. 3, p. 402-406, 2011.
0102-695X
10.1590/S0102-695X2011005000066
S0102-695X2011000300008
WOS:000292919800008
S0102-695X2011000300008.pdf
2518006820764120
4484083685251673
4702004904231248
0000-0002-1516-7765
Autor
Universidade Estadual Paulista (Unesp)
Anidro do Brasil Extrações Ltda
Resumen
Myrcia uniflora Barb. Rodr., Myrtaceae, popularly known as pedra-hume-caá in Brazil, is sold as dry extracts in capsules or as tinctures for the treatment of diabetes mellitus. Previous phytochemical studies on this species described the occurrence of the flavonoids mearnsitrin and myricitrin. In the present study, the chromatographic profiles of M. uniflora leaves and commercial extracts were determined using HPLC-PAD. Myricitrin was used as an external standard in the development and validation of the HPLC method. The proposed method is simple, rapid and reliable and can be successfully applied in industry for standardization of herbs and phytomedicines commercialised in Brazil as pedra-hume-caá.