Artigo
Intermediate reactive oxygen and nitrogen from macrophages induced by Brazilian lichens
Fecha
2004-07-01Registro en:
Fitoterapia. Amsterdam: Elsevier B.V., v. 75, n. 5, p. 473-479, 2004.
0367-326X
10.1016/j.fitote.2004.04.002
WOS:000223028800006
3538253640602977
0000-0003-3032-2556
Autor
Universidade Estadual Paulista (Unesp)
Universidade Federal de Mato Grosso do Sul (UFMS)
Resumen
The activity of ten compounds isolated from Brazilian lichen over the release of hydrogen peroxide and nitric oxide was evaluated in the culture of peritoneal macrophage cells from mice. Salazinic, secalonic A and fumarprotocetraric acids were the compounds that induced the greatest release of H2O2, whereas 12R-usnic and diffractaic acids induced the release of NO. These results indicate that lichen products have potential immunological modulating activities. (C) 2004 Elsevier B.V. All rights reserved.