O uso dos biomarcadores de genotoxidade nos estudos de exposição aos contaminantes químico ambientais

Abstract

The identification and quantification of the effects that chemicals present in the environment can cause in humans are of great importance for the assessment and prevention of health risk caused by exposure to these agents. Biomarkers are tools that enable the identification of toxic substances or their metabolites, as well as any early biochemical or structural change which estimate the risk of exposure to chemicals. Biomarkers of genotoxicity evaluate the effects of a variety of substances on the bodies which are described as carcinogenic. In this context, falls into the Comet assay and the Micronucleus Test, which assess damage to DNA caused by these chemicals.