Artículos de revistas
An efficient synthesis of new C-2 aryl substituted quinolines based on three component imino Diels-Alder reaction
Registro en:
Molecular Diversity 10 (1):29-37
1381-1991
Autor
Kouznetsov, V.V.
Bohorquez, A.R.R.
Astudillo, L.
Medina, R.F.
Institución
Resumen
Astudillo, L. Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla: 747, Talca, Chile. New effective approach to the synthesis of a wide variety of C-2 nitro or aminophenyl substituted quinolines was reported using diverse intermediate 4-(2-oxopyrrolinidyl-1)-tetrahydroquinolines that were prepared by a three component imino Diels-Alder reaction was reported. The key aromatisation process occurs cleanly with the loss of the 2-oxopyrrolinidyl-1 fragment.