Artículos de revistas
Biologically active compounds from Chilean propolis
Registro en:
Boletin De La Sociedad Chilena De Quimica 45(4): 577-581
0366-1644
Autor
Astudillo, L.
Avila, F.
Morrison, R.
Gutierrez, M.
Bastida, J.
Codina, C.
Schmeda-Hirschmann, G.
Institución
Resumen
Astudillo, L.; Avila, F.; Morrison, R.;Gutierrez, M. ; Schmeda-Hirschmann, G. Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile. A propolis sample from the western Andean slopes of the Maule Region, Chile, showed free radical scavenging activity and inhibited the enzyme xanthine oxidase "in vitro". Six flavonoids were isolated as the main active constituents of the sample. 5,7-dihydroxyflavone 4, 3,5,7-trihydroxyflavone 6 and 5,7-dihydroxyflavanone 1 displayed a strong free radical scavenging effect. At 50 mg/ml, compounds 6 and 1 inhibited the enzyme xanthine oxidase by 95 and 86%, respectively