Inflammatory biomarkers and tumoral growth factors are modulated by exercise in breast cancer survivors
Fecha
2020-12-01Registro en:
Meneses, J. F., Ramírez, R., González, E., Río, J. S. & Izquierdo, M. (s,f). Inflammatory biomarkers and tumoral growth factors are modulated by exercise in breast cancer survivors [Documento de Investigación, Universidad Santo Tomás] Repositorio Institucional - Universidad Santo Tomás
Autor
Meneses-Echávez, José Francisco
Ramírez-Vélez, Robinson
González Jiménez, Emilio
Río-Valle, Jacqueline Schmidt
Izquierdo, Mikel
Institución
Resumen
Introduction: Insulin-like growth factors (IGF´s) play a crucial role in controlling cancer cell
proliferation, differentiation and apoptosis. Exercise has been postulated as an effective
intervention in improving cancer-related outcomes and survival, although its effects on IGF´s are
not well understood. This meta-analysis aimed to determine the effects of exercise in modulating
IGF´s system in breast cancer survivors.
Methods: Databases of PuMed, EMBASE, Cochrane Central Register of Controlled Trials,
EMBASE, ClinicalTrials.gov, SPORTdiscus, LILACS and Scopus were systematically searched
up to November 2014. Effect estimates were calculated through a random-effects model of meta-
analysis according to the DerSimonian and Laird method. Heterogeneity was evaluated with the
I 2 test. Risk of bias and methodological quality were evaluated using the PEDro score.