In vivo and in vitro assessment of Lactobacillus acidophilus as probiotic for tilapia (Oreochromis niloticus, Perciformes:Cichlidae) culture improvement
Autor
Villamil, L.
Reyes, C.
Martínez-Silva, M. A.
Institución
Resumen
In this study, the use of Lactobacillus acidophilus as
a probiotic for Nile tilapia (Oreochromis niloticus)
culture was studied. Fish survival and the expression
of some genes involved in the immune
response were assessed. Diet supplementation with
L. acidophilus for 15 days caused a significant
increase in fish survival during a challenge with
Aeromonas hydrophila and variations in immune
response related to IL-1b and transferrin expression
in Nile tilapia spleen and kidney. Moreover,
extracellular products (ECPs) of L. acidophilus
showed high antibacterial activity against fish
pathogens such as A. hydrophila and Streptococcus
agalactiae in vitro. It was also observed that viable
L. acidophilus was able to disrupt quorum sensing
activity in Chromobacterium violaceum.