article
Risk of bias and confounding of observational studies of Zika virus infection: A scoping review of research protocols
Fecha
2017Registro en:
10.1371/journal.pone.0180220
Institución
Resumen
Introduction
Given the severity and impact of the current Zika virus (ZIKV) outbreak in the Americas,
numerous countries have rushed to develop research studies to assess ZIKV and its potential health consequences. In an effort to ensure that studies are comprehensive, both internally and externally valid, and with reliable results, the World Health Organization, the Pan
American Health Organization, Institut Pasteur, the networks of Fiocruz, the Consortia for
the Standardization of Influenza Seroepidemiology (CONSISE) and the International
Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) have generated six
standardized clinical and epidemiological research protocols and questionnaires to address
key public health questions on ZIKV.