masterThesis
Lactato sérico inicial y su asociación con resultados clínicos en pacientes obstetricas con sepsis en un hospital de alta complejidad
Autor
Geney Montes, Maria Cristina
Machado Santos, Jorge Javier
Institución
Resumen
Introduction: Sepsis is one of the main causes of mortality and morbidity in the obstetric population. Serum lactate has been proposed as a useful tool to determine clinical outcome of sepsis. Methods: Ambispective cohort study. 185 pregnant patients were included, in pregnancy, postpartum and post abortion with sepsis, any cause, hospitalized in critical care units at the Hospital Universitario Clinica San Rafael in Bogotá from 2014 to 2020. Serum lactate levels were determined from the first 24 hours of diagnosis. Sociodemographic and clinical characteristics and maternal outcomes were evaluated such as: longer hospital stay, longer critical care units stay, bacterial cultures, organic dysfunction, multiorgan dysfunction and maternal mortality. A descriptive and bivariate analysis was used. Results: 86 patients had a serum lactate of admission ≥ 2 mmol / L and in 99 patients it was <2 mmol /L. No statistically significant differences in the sociodemographic and clinical characteristics were found according to the value of the initial serum lactate. There were no cases of maternal deaths. No significant association was found between serum lactate levels of admission with bacterial isolation in urine culture (p = 0,918), blood culture (p = 0,154), one organ failure (p = 0,964), of more than two organ failure (p = 0,606). No statistically significant differences were found in longer stay in critical care units and longer hospital stay according to admission serum lactate (p = 0,392 and p = 0,505, respectively). Conclusions: No association was found between initial serum lactate levels and clinical outcome of sepsis in obstetric patients.