article
Association of copy number variation in the FCGR3B gene with risk of autoimmune diseases
Autor
Mamtani, M
Anaya, Juan-Manuel
He, W
Ahuja, S K
Institución
Resumen
Copy number variation (CNV) of human DNA segments is an important source of genetic diversity and increasing evidence indicates that CNV may underlie disease susceptibility.1–4 It is to be noted that there seems to be an enrichment of CNV in immune response genes1 such that they may contribute to the observed inter-individual variability in susceptibility to infectious diseases, vasculitis and autoimmune diseases