article
FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients
Autor
Rangel, Nelson
Fortunati, Nicoletta
Osella-Abate, Simona
Annaratone, Laura
Isella, Claudio
Catalano, Maria Graziella
Rinella, Letizia
Metovic, Jasna
Boldorini, Renzo
Balmativola, Davide
Ferrando, Pietro
Marano, Francesca
Cassoni, Paola
Sapino, Anna
Castellano, Isabella
Institución
Resumen
The role of forkhead-box A1 (FOXA1) and Androgen receptor (AR) in breast cancer (BC) has been extensively studied. However, the prognostic role of their co-expression in Estrogen receptor positive (ER+) BC has not been investigated so far. The aim of the present study was thus to assess the co-expression (protein and mRNA) of FOXA1 and AR in BC patients, in order to evaluate their prognostic impact according to ER status.