Artículos de revistas
Silver nanoparticles and their antibacterial applications
Fecha
2021Registro en:
Int. J. Mol. Sci. 2021, 22, 7202
10.3390/ijms22137202
Autor
Bruna, Tamara
Maldonado Bravo, Francisca
Jara Vergara, Paul Sebastián
Caro, Nelson
Institución
Resumen
Silver nanoparticles (AgNPs) have been imposed as an excellent antimicrobial agent being
able to combat bacteria in vitro and in vivo causing infections. The antibacterial capacity of AgNPs
covers Gram-negative and Gram-positive bacteria, including multidrug resistant strains. AgNPs
exhibit multiple and simultaneous mechanisms of action and in combination with antibacterial agents
as organic compounds or antibiotics it has shown synergistic effect against pathogens bacteria such
as Escherichia coli and Staphylococcus aureus. The characteristics of silver nanoparticles make them
suitable for their application in medical and healthcare products where they may treat infections or
prevent them efficiently. With the urgent need for new efficient antibacterial agents, this review aims
to establish factors affecting antibacterial and cytotoxic effects of silver nanoparticles, as well as to
expose the advantages of using AgNPs as new antibacterial agents in combination with antibiotic,
which will reduce the dosage needed and prevent secondary effects associated to both.