Artículo de revista
A multicenter, randomized comparison between 2, 5, and 8 mg of perineural dexamethasone for ultrasound-guided infraclavicular block
Fecha
2019Registro en:
Regional Anesthesia and Pain Medicine, Volumen 44, Issue 1, 2019, Pages 46-51
15328651
10987339
10.1136/rapm-2018-000032
Autor
Bravo, Daniela
Aliste, Julian
Layera, Sebastián
Fernández, Diego
Leurcharusmee, Prangmalee
Samerchua, Artid
Tangjitbampenbun, Amornrat
Watanitanon, Arraya
Arnuntasupakul, Vanlapa
Tunprasit, Choosak
Gordon, Aida
Finlayson, Roderick J.
Tran, De Q.
Institución
Resumen
© 2019 American Society of Regional Anesthesia & Pain Medicine.Background and objectives This multicenter, randomized trial compared 2, 5, and 8 mg of perineural dexamethasone for ultrasound-guided infraclavicular brachial plexus block. Our research hypothesis was that all three doses of dexamethasone would result in equivalent durations of motor block (equivalence margin=3.0 hours). Methods Three hundred and sixty patients undergoing upper limb surgery with ultrasound-guided infraclavicular block were randomly allocated to receive 2, 5, or 8 mg of preservative-free perineural dexamethasone. The local anesthetic agent (35 mL of lidocaine 1%-bupivacaine 0.25% with epinephrine 5 μg/mL) was identical in all subjects. Patients and operators were blinded to the dose of dexamethasone. During the performance of the block, the performance time, number of needle passes, procedural pain, and complications (vascular puncture, paresthesia) were recorded. Subsequently a blinded observer assessed th