Artículos de revistas
Assessment of three antimicrobial residue concentrations in broiler chicken droppings as a potential risk factor for public health and environment
Fecha
2019Registro en:
International Journal of Environmental Research and Public Health, Volumen 16, Issue 1, 2019,
16604601
16617827
10.3390/ijerph16010024
Autor
Yévenes, Karina
Pokrant, Ekaterina
Pérez, Fernando
Riquelme, Ricardo
Avello, Constanza
Maddaleno, Aldo
San Martín Núñez, Betty
Cornejo, Javiera
Institución
Resumen
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.Tetracyclines, sulfonamides and amphenicols are broad spectrum antimicrobial drugs that are widely used in poultry farming. However, a high proportion of these drugs can be excreted at high concentrations in droppings, even after the end of a therapy course. This work intended to assess and compare concentrations of florfenicol (FF), florfenicol amine (FFa), chlortetracycline (CTC), 4-epi-chlortetracycline (4-epi-CTC), and sulfachloropyridazine (SCP) in broiler chicken droppings. To this end, 70 chickens were housed under controlled environmental conditions, and assigned to experimental groups that were treated with therapeutic doses of either 10% FF, 20% CTC, or 10% SCP. Consequently, we implemented and designed an in-house validation for three analytical methodologies, which allowed us to quantify the concentrations of these three antimicrobial drugs using liquid chromatography coupled to mass spectrometry (LC-MS/MS). Our resul