Thesis
Efecto de la nutrición enteral sobre la masa magra con fórmula inmunomoduladora en pacientes con VIH/SIDA y neumonía por Pneumocystis Jiroveci
Autor
LIC. NUT. PALAFOX ÁLVAREZ, TANIA ELISA
Institución
Resumen
OBJECTIVE Verifity if the enteral nutrition with immunomodulating formula is more effective
reclaiming the nutritious state in patients with VIH/SIDA and Pneumonia by Pneumocystis jirovecci
of the Research center of infectious diseases of the National Institute of Respiratory Diseases
EXPOSITION OF THE PROBLEM. The incidence of underweight among hospitalized patients
diagnosed with HIV / AIDS and pneumonia at the National Institute of Respiratory Diseases
(INER) is high (64%) the situation may worsen the clinical picture, so early intervention is
necessary to nutritional support. Today has not evaluated the immunomodulatory effect of diet in
these patients and results in other populations such as patients with cancer, surgery, burns have been
controversial.
MATERIAL AND METHODS. Randomized, longitudinal clinical study. 30 men Majors of 18
years hospitalized, with diagnosis of VIH/SIDA and pneumonia (Pneumocystis Jirovecci),
unintentional weight loss> 5% in three months with respect to its habitual weight, conditions to
indicate enteral nutrition. They were assigned in random form to one of two groups; 1. formula with
immunomodulating enteral nutrition 2. enteral nutrition with standard nutrition; was assessed lean
body mass (kg), fat mass (%), total body weight (kg), BMI (kg/m2), days hospitalized and
adherence to dietary recall through 24 hours.
RESULTS
Both interventions were effective increasing total body weight (kg), lean mass and fat mass, as
BMI in all patients achieved the status of Normal (≥ 18.5-24.9 kg/m2) after 12 weeks ( See Table
VIII.) We can say that the immunomodulating enteral nutrition formula shows a trend toward
greater recovery of lean mass.
As for the days in the hospital there was no statistically significant difference (p = ≥ 0.05) the group
supplemented with immunomodulatory nutrition was 11 days and the standard 12 days.
CONCLUSIONS
Patients with wasting syndrome associated to AIDS require early nutritional intervention, including
complete measurement of nutrititonal parameters and dietary habits contribute to the improvement
of clinical status and reduce morbidity and mortality risks associated with malnutrition and
HIV/AIDS.