Dissertação
Eficácia de três medicamentos no controle da infecção experimental por Trypanosoma evansi em ratos (Rattus norvegicus) linhagem Wistar
Fecha
2006-03-15Registro en:
DOYLE, Rovaina Laureano. Effectiveness of three medications in the control of the experimental infection for Trypanosoma evansi in rats (Rattus norvegicus) Wistar strain. 2006. 40 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2006.
Autor
Doyle, Rovaina Laureano
Institución
Resumen
This paper aimed to describe some lab and histological findings from an experimental
infection of Trypanosoma (Trypanozoon) evansi Steel, 1885 (Balbiani, 1888) in rats (Rattus
novergicus) belonging to the Wistar strain, testing the effectiveness of three medications.
These animals were divided in 4 groups of 10 each and treated to three different chemical
treatments after the detection of more than eight tripomastigotes for visual side of the blood
smears at the light microscope with 1000 increase. Was tested injectable oxytetracycline 10%,
benzonidazol per oss and injectable diminazene 7% while one infected and untreated group
remained as control. Evaluation of treatment efficacy was performed through daily blood
smears stained by Panotico Rápido® for 60 days. The rats were necropsied aiming
histological examination. Treatment with diminazene was the most efficient since no parasites
having significant difference (p < 0.05) between males and females of that group, which
presented survive after the treatment of 14,4 days more than the males. Histological
alterations findings were not specific.