Dissertação
Cortisol, glicose e triglicerídeo na resposta neuroendócrina de cães com fratura tibial
Fecha
2011-09-30Registro en:
STURION, André Luiz Torrecillas. Cortisol, glucose, and tryglicerides in neuroendocrine response of dogs whit tibial fracture. 2011. 37 f. Dissertação (Mestrado em Medicina Veterinária) - Universidade Federal de Santa Maria, Santa Maria, 2011.
Autor
Sturion, André Luiz Torrecillas
Institución
Resumen
"Response to stress" is the designation for the set of metabolic and hormonal
changes that take place after any traumatic situation. The stress response is intended to
maintain and / or restore the homeostasis of the body injured. The major endocrine
response to stress is characterized as the increased secretion of pituitary hormones and
activation of the sympathetic nervous system. Among the pituitary hormones is ACTH,
which will sensitize the cells of the adrenal gland to secrete cortisol. The biochemical
measurements, especially cortisol and glucose has been shown to be important
references for the evaluation of pain and stress by indirect means. Therefore, the
objective of this research is to measure cortisol, the glucose and triglyceride metabolic
energy, in evaluating the neuroendocrine response of dogs with tibial fractures. For the
present study, we used 12 dogs with tibial fractures. Were colected five venous blood
samples, at the time of patient care, during the surgical procedure after induction of
anesthesia, five minutes after stimulation by periosteal implant, 24 hours after the first
collection during surgery and after seven days of the surgery. There were no statistically
significant differences between times and between the values of cortisol, glucose and
triglycerides, but there was a numerical difference between the mean times analyzed, we
observed that the cortisol showed an average decrease between times. The mean glucose
values had increased in the pre and trans-surgical times, and with a decrease in mean
postoperative periods. Mean triglyceride values varied widely between periods. It is
possible to conclude that cortisol is an important mediator in the neuroendocrine
response of dogs with acute tibial fractures, the mean values of glucose did not respond
similarly to cortisol during surgical procedures and that the triglyceride is not a good
parameter for evaluating the neuroendocrine stress dogs with acute tibial fractures.