Artigo
Flavonoids and fatty acids of Camellia japonica leaves extract
Fecha
2011-12-01Registro en:
Revista Brasileira de Farmacognosia. Sociedade Brasileira de Farmacognosia, v. 21, n. 6, p. 1159-1162, 2011.
0102-695X
S0102-695X2011000600030.pdf
S0102-695X2011000600030
10.1590/S0102-695X2011005000128
WOS:000297216900030
Autor
Azuma, Cinthia Midori
Santos, Flávia Cristina S. dos
Lago, Joao Henrique Ghilardi [UNIFESP]
Institución
Resumen
The ethanol extract from the leaves of Camellia japonica L., Theaceae, showed antiradical potential in the DPPH test using TLC plates (SiO2). Aiming the isolation of active compounds, this extract was partitioned between BuOH:H2O (1:1) and the two obtained phases were also evaluated to detection of antiradical activity. The active BuOH phase was fractionated in Sephadex LH-20 and silica (normal or reverse phase) to afford three aglycone flavonoids (quercetin, kaempferol and apigenin), which have been described in the C. japonica at first time, two glycosilated flavonoids (rutin and quercetrin), and a mixture of saturated fatty acids. The structures of isolated compounds were defined by NMR and GC/MS analyses.