Artículos de revistas
Response predictors to treatment with pegylated interferon in chronic hepatitis B
Fecha
2010-10-01Registro en:
Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 14, n. 5, p. 519-525, 2010.
1413-8670
S1413-86702010000500017.pdf
S1413-86702010000500017
10.1590/S1413-86702010000500017
WOS:000286107300017
Autor
Ferreira, Paulo Roberto Abrão
Tenore, Simone de Barros
Institución
Resumen
The clinical and epidemiological importance of chronic B hepatitis is currently unquestionable as a cause of end-stage liver disease and hepatocellular carcinoma. Recently, predictors of treatment response of this disease have been studied, both before and during the course of medication. Therapy stopping rules have been proposed, which may be useful in patients presenting poor treatment tolerance. This review discusses the treatment response predictors usefulness, with emphasis on ALT, quantitative HBsAg and HBeAg, quantitative HBV-DNA and HBV genotype