Artículos de revistas
The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis
Fecha
2001-02-01Registro en:
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 34, n. 2, p. 145-154, 2001.
0100-879X
S0100-879X2001000200001.pdf
S0100-879X2001000200001
10.1590/S0100-879X2001000200001
WOS:000167337600001
Autor
Andreatini, R.
Blanchard, C.
Blanchard, R.
Brandão, M.l.
Carobrez, A.p.
Griebel, G.
Guimarães, F.s.
Handley, S.l.
Jenck, F.
Leite, Jose Roberto
Rodgers, J.
Schenberg, L.c.
Da Cunha, C.
Graeff, F.g.
Institución
Resumen
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification.