Artículos de revistas
Physical exercise, IGF-1 and cognition: A systematic review of experimental studies in the elderly
Exercício físico, IGF-1 e cognição: Uma revisão sistemática de estudos experimentais em idosos
Fecha
2018-04-01Registro en:
Dementia e Neuropsychologia, v. 12, n. 2, p. 114-122, 2018.
1980-5764
10.1590/1980-57642018dn12-020003
S1980-57642018000200114
2-s2.0-85048822677
S1980-57642018000200114.pdf
Autor
Universidade Estadual Paulista (Unesp)
Instituto Federal Goiano
Federal University of Triangulo Mineiro
Universidade Federal do ABC (UFABC)
Institución
Resumen
One of hypothetical mechanisms related to cognition is exercise-induced IGF-1. Objective: The aim of this study was to analyze the effects of exercise on IGF-1 levels and cognition in the elderly. Methods: The article searches were conducted on Pubmed, Web of Science, PsycINFO and Scielo databases and reviewed according to PRISMA guidelines. The inclusion criteria were: [1] original articles published up to 2017; [2] samples including elderly; [3] protocols including physical exercise; [4] longitudinal studies having exercise as main outcome; [5] assessment of IGF-1; [6] cognition assessment. Results: Seven studies were included in this review. Three of the studies showed an exercise-induced increase in IGF-1; three found stable IGF-1 levels and one found a reduction in IGF-1; with and without improvement in cognition. Conclusion: Disparities in the type of physical exercise, protocols and samples under different conditions hinder the establishment of a consensus on IGF-1, cognition and physical exercise.