Artículos de revistas
Syndrome in question: Antisynthetase syndrome (anti-PL-7)
Fecha
2016-09-01Registro en:
Anais Brasileiros de Dermatologia, v. 91, n. 5, p. 679-681, 2016.
1806-4841
0365-0596
10.1590/abd1806-4841.20164449
S0365-05962016000500683
2-s2.0-84994619760
S0365-05962016000500683.pdf
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Antisynthetase syndrome is a rare autoimmune disease characterized by interstitial lung disease and/or inflammatory myositis, with positive antisynthetase antibodies (anti-Jo-1, anti-PL-7, anti-PL-12, ZO, OJ, anti-KE or KS). Other symptoms described include: non-erosive arthritis, fever, Raynaud’s phenomenon, and mechanic’s hands. The first therapeutic option is corticotherapy, followed by other immunosuppressants. The prognosis of the disease is quite limited when compared to other inflammatory myopathies with negative antisynthetase antibodies.