Actas de congresos
The participation of singlet oxygen in a photocitotoxicity of extract from amazon plant to cancer cells
Fecha
2017-01-01Registro en:
Proceedings of SPIE - The International Society for Optical Engineering, v. 10456.
1996-756X
0277-786X
10.1117/12.2283317
2-s2.0-85040720966
2-s2.0-85040720966.pdf
Autor
Interdisciplinary Reference Centre
Biotecnologia e Biodiversidade
Universidade Estadual Paulista (Unesp)
Herminio Ometto University Center (FHO UNIARARAS)
Paulista University (UNIP)
Institución
Resumen
We have been searching for new photosensitizers (PS) for photodynamic therapy (PDT) of cancer based on extracts from Amazonian plants since 2009. In this paper, we demonstrate that, under certain conditions, the extract from fruits of the Amazonian palm Euterpe oleraceae (popular name Açaí) can serve as a PS for PDT treatment of murine breast cancer cells (4T1 cell line). We have been first to show directly that the photodynamic effect of plant PS is due to singlet oxygen.