Hemoglobin (Hb) Val de Marne (Hb Footscray) in Brazil: the first case report

Artículos de revistas

Fecha

2016-01-01

Registro en:

Genetics And Molecular Research. Ribeirao Preto: Funpec-editora, v. 15, n. 2, 8 p., 2016.

1676-5680

http://hdl.handle.net/11449/162013

10.4238/gmr.15028294

WOS:000384881000091

3279428066176719

0000-0002-4603-9467

Autor

Universidade Estadual Paulista (Unesp)

Universidade Estadual de Maringá (UEM)

Institución

Universidade Estadual Paulista (Brasil)

Resumen

Hemoglobin (Hb) variants involving alpha-chains are less common in the global population than Hb variants resulting from beta-chain alterations. Generally, alpha-chain Hb variants are caused by point mutations affecting alpha-1 and/or alpha-2 genes of the alpha-globin cluster (HBA1 and HBA2). In Brazil, the most prevalent alpha-chain Hb variant is Hb Hasharon. In this study, we present the first case of an Hb Val de Marne variant in the Americas, specifically in Brazil.

Materias

Hemoglobin variants

Alpha-globin

HPLC

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