Artículos de revistas
ONE-POT SYNTHESIS OF ISOQUINUCLIDINE DERIVATIVES THROUGH MULTICOMPONENT AZA-DIELS-ALDER REACTIONS PROMOTED BY NIOBIUM PENTAETHOXIDE
Date
2015-01-01Registration in:
Heterocyclic Letters. Jaipur: Raman Publ, v. 5, n. 3, p. 431-442, 2015.
2231-3087
WOS:000373301800017
Author
Universidade Estadual Paulista (Unesp)
Institutions
Abstract
The bicyclic isoquinuclidine system can be found in many natural products and has several pharmacological properties. In this paper is described an one-pot sysnthesis of Isoquinuclidine derivatives through multicomponent aza-Diels-Alder reactions between aniline derivatives, benzaldehyde and 2-cyclohexenone, promoted by niobium pentaethoxide under mild conditions, affording the expected products in high yields.