Artículos de revistas
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats
Fecha
2010Registro en:
Journal of Applied Oral Science, v. 18, n. 3, p. 237-243, 2010.
1678-7757
10.1590/S1678-77572010000300007
S1678-77572010000300007
S1678-77572010000300007.pdf
0047062193534190
4774447118127346
4068921369233125
Autor
Universidade Estadual Paulista (Unesp)
Universidade Federal do Piauí (UFPI)
Centro Universitário da Fundação Educacional de Barretos (UNIFEB)
Institución
Resumen
OBJECTIVE: The aim of this study was to assess radiographically the effect of photodynamic therapy (PDT) as an adjunctive treatment to scaling and root planing (SRP) on induced periodontitis in dexamethasone-induced immunosuppressed rats. MATERIAL AND METHODS: The animals were divided into 2 groups: ND group (n=60): saline treatment; D group (n=60): dexamethasone treatment. In both ND and D groups, periodontal disease was induced by the placement of a ligature in the left first mandibular molar. After 7 days, ligature was removed and all animals received SRP, being divided according to the following treatments: SRP: saline and PDT: phenothiazinium dye (TBO) plus laser irradiation. Ten animals per treatment were killed at 7, 15 and 30 days. The distance between the cementoenamel junction and the height of the alveolar bone crest in the mesial surface of the mandibular left first molars was determined in millimeters in each radiograph. he radiographic values were analyzed statistically by ANOVA and Tukey's test at a p value <0.05. RESULTS: Intragroup radiographic assessment (ND and D groups) showed that there was statistically signifcant less bone loss in the animals treated with PDT in all experimental periods compared to those submitted to SRP. Intergroup radiographic analysis (ND and D groups) demonstrated that there was greater bone loss in the ND group treated with SRP compared to the D group treated with PDT at 7 and 30 days. CONCLUSION: PDT was an effective adjunctive treatment to SRP on induced periodontitis in dexamethasone-induced immunosuppressed rats.