Artículos de revistas
On-line monitoring of electrochemical degradation of paracetamol through a biomimetic sensor
Fecha
2011Registro en:
International Journal of Electrochemistry, v. 2011, p. 1-11, 2011.
2090-3529
10.4061/2011/171389
ISSN2090-3529-2011-2011-01-11.pdf
2933194342093387
7461419671865423
3358026922931043
2933194342093387
Autor
Universidade Estadual Paulista (Unesp)
Universidade de São Paulo (USP)
Universidade Estadual de Campinas (UNICAMP)
Institución
Resumen
This paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with a DSA anode. The process efficiency was monitored at real time by the biomimetic sensor constructed by modifying a glassy carbon electrode with a Nafion membrane doped with iron tetrapyridinoporphyrazine (FeTPyPz). Simultaneously, we carried out off-line analysis by liquid chromatography (HPLC) during the experiments in order to validate the proposed system. In addition, to investigate the degradation products of the paracetamol electrolysis, we used the techniques of UPLC/MS and GC/MS.