Artículos de revistas
Unusual C,O-fused glycosylapigenins from Serjania marginata leaves
Fecha
2014Registro en:
Journal of Natural Products, v. 78, n. 1, p. 77-84, 2014.
0163-3864
10.1021/np500715x
7927877224326837
0000-0003-3032-2556
Autor
Universidad de Cádiz
Universidade Estadual Paulista (Unesp)
Institución
Resumen
A phytochemical study of a Serjania marginata leaf extract with antiulcer activity afforded 15 compounds, including the new 3-O-α-l-arabinopyranosyl(1→3)-α-l-rhamnopyranosyl(1→2)[β-d-glucopyranosyl(1→4)]-α-l-arabinopyranosyloleanolic acid (1) and 7,5″-anhydroapigenin 8-C-α-(2,6-dideoxy-5-hydroxy-ribo-hexopyranosyl)-4′-O-β-d-glucopyranoside (4). The structures of the new compounds were determined by spectroscopic analysis, including 1D and 2D NMR techniques, mass spectrometry, and chemical methods. Compound 4 is a C-hexopyranosylapigenin with an unusual cyclic ether linkage between C-5″ and C-7 of apigenin. The isolated proanthocyanidins have high antioxidant activities, and these compounds are probably responsible for the gastroprotective effect of the extract.