Artículos de revistas
Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi
Fecha
2014-01-01Registro en:
Evidence-based Complementary And Alternative Medicine. New York: Hindawi Publishing Corporation, 8 p., 2014.
1741-427X
10.1155/2014/506273
WOS:000345755800001
WOS000345755800001.pdf
WOS000345755800001.epub
4702004904231248
4484083685251673
0000-0002-8059-0826
Autor
Universidade Estadual Paulista (Unesp)
Institución
Resumen
This work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity against several species of pathogenic fungi, mainly, Candida spp., Cryptococcus spp., Paracoccidioides spp., and Histoplasma capsulatum, according to standardized microdilution method described by Clinical Laboratory Standard Institute (CLSI) documents. Moreover this compound has a particularly good selectivity index value, which makes it an excellent candidate for broad-spectrum antifungal prototype and encourages the continuation of subsequent studies for the discovery of its mechanism of action.