Artículos de revistas
Synthesis, crystal structures, antimicrobial, antifungal and antituberculosis activities of mixed ligand silver(I) complexes
Fecha
2013-10-14Registro en:
Polyhedron, v. 62, p. 138-147.
0277-5387
10.1016/j.poly.2013.06.021
WOS:000324226200018
2-s2.0-84885104441
2114570774349859
Autor
King Fahd University of Petroleum and Minerals
University of Neuchâtel
Universidade Federal de Juiz de Fora (UFJF)
Instituto Adolfo Lutz (IAL)
Universidade Estadual Paulista (Unesp)
University of Engineering and Technology
Faculté des Sciences
Institución
Resumen
The biological activity of some new mixed silver-phosphane-thio-ligand complexes, with 1:1:2, 1:1:1 and 1:2:1 (Ag:phospine:ligand) compositions, have been examined. Ten compounds were prepared using a series of silver(I) salts [AgX, where X = NO3, ClO4, PF6 and Br], tertiary phosphines and the ligands thi-osemicarbazide, 2-(propan-2-ylidene) hydrazinecarbothioamide, and thiazolidine-2-thione. The syntheses were carried out under ambient conditions, and the ten complexes obtained were found to be light stable. All 10 compounds were characterized by elemental analysis, FTIR, and NMR spectroscopy, whereas nine compounds were characterized by X-ray diffraction analysis. The anti-proliferative activities were evaluated by minimum inhibitory concentration (MIC: lg/mL) in an aqueous suspension system and they all show promising potential activity against selective strains of Gram-positive and Gram-negative bacteria, fungous and Mycrobaterium tuberculosis H37Rv. © 2013 Elsevier Ltd. All rights reserved.