Artículos de revistas
Qualidade de vida em portadores de esclerose múltipla
Fecha
2007-06-01Registro en:
Arquivos de Neuro-Psiquiatria, v. 65, n. 2 B, p. 454-460, 2007.
0004-282X
1678-4227
10.1590/S0004-282X2007000300018
S0004-282X2007000300018
WOS:000248225000018
2-s2.0-34547614610
2-s2.0-34547614610.pdf
4044986284615753
Autor
Universidade Federal de Uberlândia (UFU)
BCTRIMS (Comitê Brasileiro de Tratamento e Pesquisa em Esclerose Múltipla)
BCTRIMS
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Multiple sclerosis (MS) is a chronic disease which may exert significant effects on the life of patients. Traditional outcome measures in MS lack in consider the effects of the disease on health-related quality of life (HRQoL). The goal of this study is to measure HRQoL in MS patients in the city of Uberlân-dia, State of Minas Gerais, Brazil. The Brazilian version of the SF-36 was applied in 23 MS patients and in 69 subjects of general population (blood donors) in Uberlândia. MS patients scored lower in all SF-36 scales than do the general population, principally in physical function domains. Patients with EDSS scores ≤3.5 had higher mean scores in four domains than do the patients with EDSS scores ≥4.0, and lower in all domains than control group. Depressive symptoms and heat intolerance showed correlation with SF-36 domains and components. In conclusion, MS patients have a significant negative impact on all HRQoL domains measured by SF-36, compared with general population, even in the stages with lower disability.