Artículos de revistas
Determination of the sodium monofluoroacetate in serum by gas chromatography
Fecha
2001-09-01Registro en:
Chromatographia. Wiesbaden: Vieweg, v. 54, n. 5-6, p. 402-404, 2001.
0009-5893
10.1007/BF02492692
WOS:000171316600020
4659698040759224
Autor
Universidade do Sagrado Coração (USC)
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Sodium monofluoroacetate (NAFAc) has been widely used for vertebrate pest control, such as rabbits in Australia. However NAFAc is extremely toxic to all vertebrates and its use is restricted. Although this compound is stringently restricted, the occurrence of accidental and homicidal poisoning is no ever-present possibility.The method developed in this work shows the applicability of SPE with alumina cartridges for the extraction of NAFAc from serum samples. The method is efficient with recoveries of at least 96.8% from spiked serum. The samples were subsequently derivatized with dicyclohexylcabodiimide (DCC), using 2,4-dichloroaniline (DCA), to make the product volatile for GC analysis.