Artículos de revistas
Determination of iodide and idoxuridine at a glutaraldehyde-cross-linked poly-L-lysine modified glassy carbon electrode
Fecha
2005-07-01Registro en:
Electroanalysis. Weinheim: Wiley-v C H Verlag Gmbh, v. 17, n. 14, p. 1309-1316, 2005.
1040-0397
10.1002/elan.200403247
WOS:000230874700010
0072173018005712
0000-0002-2296-1393
Autor
Universidade Estadual Paulista (Unesp)
Univ Luton
Univ Loughborough
Univ Ca Foscari Venezia
Institución
Resumen
The detection limit (about 0.017 mu g mL(-1)) for voltammetric determination of iodide (peak at +0.87 V vs. Ag/AgCl at pH 2) at a glutaraldehyde-cross-linked poly-L-lysine modified glassy carbon electrode involving oxidation to iodine was found to be several orders of magnitude lower than that for the voltammetric determination on a bare glassy carbon electrode. This method was applied successfully to the determination of iodide in two medicinal formulations. Idoxuridine was determined indirectly at the same electrode by accumulating it first at -0.8 V vs. Ag/AgCl. At this potential the C-I bond in the adsorbed idoxuridine is reduced giving iodide, which is then determined at the modified electrode. The method was successfully applied to the determination of idoxuridine in a urine sample.