A high-performance liquid chromatographic assay for sparfloxacin

Artículos de revistas

Date

1999-07-01

Registration in:

Journal of Pharmaceutical and Biomedical Analysis. Oxford: Pergamon-Elsevier B.V., v. 20, n. 3, p. 413-417, 1999.

0731-7085

http://hdl.handle.net/11449/36822

10.1016/S0731-7085(98)00102-2

WOS:000080819800001

http://repositorioslatinoamericanos.uchile.cl/handle/2250/2546125

Author

Universidade Estadual Paulista (UNESP)

Universidade Federal do Rio Grande do Sul (UFRGS)

Institutions

Universidade Estadual Paulista (Brasil)

Abstract

A specific and sensitive high-performance liquid chromatographic procedure was developed for the assay of sparfloxacin in raw material and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery. This method can also be applied to stability studies. (C) 1999 Elsevier B.V. B.V. All rights reserved.

Subjects

fluoroquinolone

HPLC

quality control

sparfloxacin

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