Artículos de revistas
Preparation and antimicrobial activity of gelatin microparticles containing propolis against oral pathogens
Fecha
2006-01-01Registro en:
Drug Development and Industrial Pharmacy. Philadelphia: Taylor & Francis Inc., v. 32, n. 2, p. 229-238, 2006.
0363-9045
10.1080/03639040500466312
WOS:000235652200009
Autor
Universidade de São Paulo (USP)
Univ Franca
Fac Odontol Ribeirao Preto
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Gelatin microparticles containing propolis ethanolic extractive solution were prepared by spray-drying technique. Particle,, with regular morphology, mean diameter ranging of 2.27 mu m to 2.48 mu m, and good entrapment efficiency for propolis were obtained. The in vitro antimicrobial activity of microparticles was evaluated against microorganisms of oral importance (Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus mitis, Streptococcus mutans, Streptococcus sobrinus, Candida albicans, and Lactobacillus casei). The utilized techniques were diffusion in agar and determination of minimum inhibitory concentration. The choice of the method to evaluate the antimicrobial activity of microparticles showed be very important. The microparticles displayed activity against all tested strains of similar way to the propolis, showing greater activity against the strains of E. salivarius, S. sanguinis, S. mitis, and C albicans.