Artículos de revistas
Aplicação e avanços da espectroscopia de luminescência em análises farmacêuticas
Fecha
2008-01-01Registro en:
Química Nova. Sociedade Brasileira de Química, v. 31, n. 7, p. 1755-1774, 2008.
0100-4042
10.1590/S0100-40422008000700031
S0100-40422008000700031
WOS:000262432800031
S0100-40422008000700031.pdf
2933194342093387
Autor
Universidade Estadual Paulista (Unesp)
Universidade São Francisco
Universidade Estadual de Campinas (UNICAMP)
Institución
Resumen
This paper provides a review on the latest advances and applications of the luminescence spectroscopy for the development of pharmaceuticals analyses methods, basically based on the photo- and chemiluminescence. The different forms of the drugs determination on pharmaceuticals through the fluorescence and chemiluminescence are discussed. The analyses include the drugs native fluorescence (liquid and solid-phases); the fluorescence from the oxidizing or reducing forms of the drug; the fluorescence from the chemical derivatization and their photochemistry and hydrolysis reactions. The quenching of luminescence and chemiluminescence generation for the pharmaceutical quantification are also shown. Finally, the trends and future perspectives of the luminescence spectroscopy in the field of the pharmaceutical research are discussed.