Artículos de revistas
Spontaneous vesicles of sodium dihexadecylphosphate in HEPES buffer
Date
2008-04-15Registration in:
Journal of Colloid and Interface Science. San Diego: Academic Press Inc. Elsevier B.V., v. 320, n. 2, p. 608-610, 2008.
0021-9797
10.1016/j.jcis.2008.02.007
WOS:000254351600030
Author
Universidade Estadual Paulista (Unesp)
Institutions
Abstract
The formation of spontaneous vesicles of dihexadecylphosphate (DHP) in a HEPES buffered solution at pH 7.4, the size, morphology and melting temperature, obtained by cryogenic transmission electron microscopy (cryo-TEM) and differential scanning calorimetry (DSC), are reported. The vesicles were formed by simply mixing a 5.0 mM lipid-solvent mixture at a temperature (75 degrees C) safely above the higher melting temperature T-m = 70.4 degrees C of DHP. The vesicle diameter ranges from 100 to 332 nm and their geometry is spherical, faceted or oblong. T-m increases from 66.8 to 70.4 as DHP concentration is raised from 0.6 to 5.0 mM. (c) 2008 Elsevier B.V. All rights reserved.