Artículos de revistas
Saccade-related modulations of neuronal excitability support synchrony of visually elicited spikes
Fecha
2011Registro en:
Cerebral Cortex, Volumen 21, Issue 11, 2018, Pages 2482-2497
10473211
14602199
10.1093/cercor/bhr020
Autor
Ito, Junji
Maldonado Arbogast, Pedro
Singer, Wolf
Grün, Sonja
Institución
Resumen
During natural vision, primates perform frequent saccadic eye movements, allowing only a narrow time window for processing the visual information at each location. Individual neurons may contribute only with a few spikes to the visual processing during each fixation, suggesting precise spike timing as a relevant mechanism for information processing. We recently found in V1 of monkeys freely viewing natural images, that fixation-related spike synchronization occurs at the early phase of the rate response after fixation-onset, suggesting a specific role of the first response spikes in V1. Here, we show that there are strong local field potential (LFP) modulations locked to the onset of saccades, which continue into the successive fixation periods. Visually induced spikes, in particular the first spikes after the onset of a fixation, are locked to a specific epoch of the LFP modulation. We suggest that the modulation of neural excitability, which is reflected by the saccade-related LFP ch