Artículo de revista
Azathioprine in the management of autoimmune uveitis
Fecha
2008Registro en:
Ocular Immunology and Inflammation, Volumen 16, Issue 4, 2018, Pages 161-165
09273948
17445078
10.1080/09273940802204519
Autor
Pacheco, Patricio A.
Taylor, Simon R.J.
Cuchacovich Turteltaub, Miguel
Diaz, Gonzalo V.
Institución
Resumen
Purpose: To evaluate the role of azathioprine as an immunosuppressive for steroid-resistant autoimmune uveitis (AIU). Methods: Patients using oral prednisolone for active AIU without clinical response were recruited. A standard protocol of oral prednisolone and azathioprine was used. Results: Twenty-seven patients participated in the study: 3 with anterior uveitis, 1 pars planitis, 4 idiopatic panuveitis, 8 Vogt-Koyonagi-Harada syndrome, 3 Behcet disease, and 8 choroidoretinopathies. Complete response was observed in 92%. Eleven patients had well-tolerated minor side effects. Conclusion: Azathioprine is safe and effective in controlling steroid-resistant AIU. Copyright © Informa Healthcare USA, Inc.