Artículo de revista
Pharmacological actions of substance P in the rat vas deferens
Fecha
1991Registro en:
Neuropeptides, Volumen 18, Issue 4, 2018, Pages 209-213
01434179
10.1016/0143-4179(91)90149-D
Autor
Miranda, H. F.
Silva, W. I.
Wolstenholme, W. W.
Cuevas, N.
Ucros, A.
Bustamante, D.
Fernández, E. H.
Institución
Resumen
SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth muscle (NK-3 receptor). 2) A neurogenic effect at the pre-synaptic level that results from stimulation of another subtype of SP receptor, located on the nerve terminals (NK-1 receptor). © 1991.