dc.creator | Luchsinger, Vivian | |
dc.creator | Vásquez, Patricia | |
dc.creator | Silva, Matías | |
dc.creator | José Bruno, M. | |
dc.creator | Siches, Izkia | |
dc.creator | Villarroel, Javier | |
dc.creator | Luisa Garmendia, M. | |
dc.creator | Larrañaga, Carmen | |
dc.date.accessioned | 2019-01-29T15:38:17Z | |
dc.date.available | 2019-01-29T15:38:17Z | |
dc.date.created | 2019-01-29T15:38:17Z | |
dc.date.issued | 2015 | |
dc.identifier | Revista Chilena de Infectologia, Volumen 32, Issue 6, 2018, Pages 664-671 | |
dc.identifier | 07161018 | |
dc.identifier | 10.4067/S0716-10182015000700008 | |
dc.identifier | https://repositorio.uchile.cl/handle/2250/161851 | |
dc.description.abstract | © 2015, Sociedad Chilena de Infectologia. All rights reserved.Background: Cytomegalovirus (CMV) infection is frequent in HIV adults. It is unknown usefulness of quantitative methods for diagnosing the CMV disease in Chilean patients. Aim: To determine the performance of antigenemia and real time polymerase chain reaction (rtPCR) in the diagnosis of CMV disease in Chilean HIV adults. Method: Detection of CMV by viral isolation (AVR), antigenemia and quantitative rtPCR in HIV adults. Results: The 102 adults with suspected CMV disease had lower LTCD4 count and higher HIV viral load than 77 patients without suspicion (p < 0.05). Antigenemia and PCR were positive in 47 (46.1%) and 37 (36.3%) adults with clinical suspicion and in 2 (2.6%) and 4 (5.2%) of 77 without suspicion. The sensitivity, specificity, positive and negative predictive value of antigenemia and RPCtr were 92%, 80%, 72% and 95% and 72%, 95%, 92% and 80%, respectively. The cutoff values were ≥ 1cell (+) and ≥ 5.5 log10 copies | |
dc.language | en | |
dc.publisher | Sociedad Chilena de Infectologia | |
dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
dc.source | Revista Chilena de Infectologia | |
dc.subject | Antigenemia | |
dc.subject | Cytomegalovirus | |
dc.subject | HIV | |
dc.subject | Real time polymerase chain reaction | |
dc.title | Antigenemia and real time polymerase chain reaction for diagnosis of cytomegalovirus disease in HIV infected adults Antigenemia y reacción de polimerasa en cadena en tiempo real en el diagnóstico de enfermedad por citomegalovirus en adultos con virus de i | |
dc.type | Artículos de revistas | |