Artículos de revistas
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations
Fecha
2010Registro en:
Annals of Human Genetics, Volumen 74, Issue 6, 2018, Pages 525-538
14691809
00034800
10.1111/j.1469-1809.2010.00608.x
Autor
Yang, Ning Ning
Mazières, Stephane
Bravi, Claudio
Ray, Nicolas
Wang, Sijia
Burley, Mari Wyn
Bedoya, Gabriel
Rojas, Winston
Parra, Maria V.
Molina, Julio A.
Gallo, Carla
Poletti, Giovanni
Hill, Kim
Hurtado, Ana M.
Petzl-Erler, Maria L.
Tsuneto, Luiza T.
Kl
Institución
Resumen
We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These da