Artículo de revista
Bone marrow ribonucleic acid polymerase. Effect of testosterone on nucleotide incorporation into nuclear RNA
Fecha
1976Registro en:
Nucleic Acids Research, Volume 3 no.11 November 1976
03051048
10.1093/nar/3.11.3077
Autor
Valladares Boasi, Luis
Cañas, Patricio E.
Minguell, José J.
Institución
Resumen
The incorporation of 3H UTP into RNA by isolated rat bone marrow nuclei is stimulated by testosterone. This effect is hormone and tissue specific. Using α amanitine and different ionic strength conditions it was found that testosterone enhances preferentially RNA polymerase I activity. The sedimentation pattern of RNA isolated from bone marrow nuclei shows that the synthesis of RNA species within the 14 to 30 S range is mainly stimulated by the hormone.