Artículo de revista
Stability of a per os ciprofloxacin formulation ESTABILIDAD DE UNA FORMULACION ORAL DE CIPROFLOXACINA
Acta Farmaceutica Bonaerense, Volumen 12, Issue 3, 2018, Pages 149-154
A stability study of a ciprofloxacin tablet formulation was performed. For the stability study, samples of tablets were stored during a six month period both at room conditions and under 37°C of relative humidity; after this time degradation products were determined and weight variation, desintegration time, hardness, friability and dissolution kinetics were evaluated. The ANOVA method, and the Dunnet Test (p < 0.01) were used for the statistical analysis. Good stability tablet characteristics in some galenical properties observed after storing the tablets at 37°C and 75% humidity did not affect their dissolution properties.