Artículo de revista
Effect of morphine‐induced cortical excitation on spinal sensory transmission
Fecha
1986Registro en:
Journal of Neuroscience Research, Volumen 15, Issue 2, 2018, Pages 217-222
10974547
03604012
10.1002/jnr.490150211
Autor
Hernández, Alejandro
Soto Moyano, Rubén
Institución
Resumen
Bioelectrical responses evoked in the ventrolateral funiculus (VLF) of the spinal cord by electrical stimulation of the contralateral hind limb were studied following topical application of 1% morphine solution to the somatosensory SI area of the rat cerebral cortex. After morphine, a typical pattern was observed in the electrocorticogram, characterized by the appearance of rhythmic spiking activity. Time‐related with each cortical spike, a significant reduction in the amplitude of VLF responses was observed. It is concluded that cortical excitation induced by morphine generates descending influences having the ability to inhibit spinal sensory transmission. Copyright © 1986 Alan R. Liss, Inc.