Artículo de revista
Prevalencia del virus papiloma humano en pacientes con diagnóstico de carcinoma escamoso de la cavidad oral
Fecha
2016Registro en:
Revista Chilena de Cirugia, Volumen 68, Issue 2, 2016, Pages 137-142.
07184026
03793893
10.4067/S0718-40262016000200005
Autor
Pennacchiotti, Gina
Sáez, Raúl
Martínez, María
Cárcamo, Marcela
Montes, Rodrigo
Institución
Resumen
Aim: To establish the prevalence of HPV in patients with diagnose of Oral Squamous cell carcinoma,
treated in the Instituto Nacional del Cáncer in fresh tumoral samples. Methods: Cross-sectional study. The
inclusion criteria were patients over 18 years, histological diagnosis of Oral Squamous cell carcinoma, that
haven’t received any previous cancer treatment, in normal physical and mental conditions. All patients signed
an informed consent. Samples consisting of fresh biopsies of lesions with clinical and pathological diagnosis
were made. The samples were processed in the Programme of Virology, Faculty of Medicine, Universidad de
Chile, through PCR and genotyped by Linear Array® (ROCHE). Results: The prevalence of VPH obtained in
this patients was of 9.09% (2/22), corresponding 1 to VPH 56. The positive patients for VPH resulted to be a
man of 35 years and a woman of 73 years (9%). Conclusion: The prevalence of HPV in this type of patients
was 9.09%, similar than the international publications.