Artículos de revistas
Analysis of 25 C NBOMe in Seized Blotters by HPTLC and GC-MS
Fecha
2016Registro en:
Journal of Chromatographic Science, Volumen 54, Issue 7, 2018, Pages 1153-1158
00219665
10.1093/chromsci/bmw095
Autor
Duffau, Boris
Camargo, Cristian
Kogan Bocian, Marcelo
Fuentes, Edwar
Cassels Niven, Bruce
Institución
Resumen
© 2016 The Author 2016. Published by Oxford University Press.Use of unauthorized synthetic drugs is a serious, forensic, regulatory and public health issue. In this scenario, consumption of drug-impregnated blotters is very frequent. For decades, blotters have been generally impregnated with the potent hallucinogen known as lysergic acid diethylamide (LSD); however, since 2013 blotter stamps with N-2 methoxybenzyl-substituted phenylethylamine hallucinogen designated as "NBOMes" have been seized in Chile. To address this issue with readily accessible laboratory equipment, we have developed and validated a new HPTLC method for the identification and quantitation of 25-C-NBOMe in seized blotters and its confirmation by GC-MS. The proposed method was validated according to SWGTOX recommendations and is suitable for routine analysis of seized blotters containing 25-C-NBOMe. With the validated method, we analyzed 15 real samples, in all cases finding 25-C-NBOMe in a wide dosage range (701.0-